Direct interaction of TrkA/CD44v3 is essential for NGF-promoted aggressiveness of breast cancer cells

BACKGROUND: CD44 is a multifunctional membrane glycoprotein. Through its heparan sulfate chain, CD44 presents growth factors to their receptors. We have shown that CD44 and Tropomyosin kinase A (TrkA) form a complex following nerve growth factor (NGF) induction. Our study aimed to understand how CD4...

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Detalles Bibliográficos
Autores principales: Trouvilliez, Sarah, Cicero, Julien, Lévêque, Romain, Aubert, Léo, Corbet, Cyril, Van Outryve, Alexandre, Streule, Karolin, Angrand, Pierre-Olivier, Völkel, Pamela, Magnez, Romain, Brysbaert, Guillaume, Mysiorek, Caroline, Gosselet, Fabien, Bourette, Roland, Adriaenssens, Eric, Thuru, Xavier, Lagadec, Chann, de Ruyck, Jérôme, Orian-Rousseau, Véronique, Le Bourhis, Xuefen, Toillon, Robert-Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962522/
https://www.ncbi.nlm.nih.gov/pubmed/35346305
http://dx.doi.org/10.1186/s13046-022-02314-4

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