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N-glycolylneuraminic acid serum biomarker levels are elevated in breast cancer patients at all stages of disease

BACKGROUND: Normal human tissues do not express glycans terminating with the sialic acid N-glycolylneuraminic acid (Neu5Gc), yet Neu5Gc-containing glycans have been consistently found in human tumor tissues, cells and secretions and have been proposed as a cancer biomarker. We engineered a Neu5Gc-sp...

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Detalles Bibliográficos
Autores principales: Shewell, Lucy K., Day, Christopher J., Kutasovic, Jamie R., Abrahams, Jodie L., Wang, Jing, Poole, Jessica, Niland, Colleen, Ferguson, Kaltin, Saunus, Jodi M., Lakhani, Sunil R., von Itzstein, Mark, Paton, James C., Paton, Adrienne W., Jennings, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962556/
https://www.ncbi.nlm.nih.gov/pubmed/35346112
http://dx.doi.org/10.1186/s12885-022-09428-0