Cargando…
Validation of a novel quality of life questionnaire: the Digestion-associated Quality of Life Questionnaire (DQLQ)
BACKGROUND: Few health-related quality of life (QOL) questionnaires are designed specifically for healthy populations and are specific to gastrointestinal (GI) symptoms even though healthy individuals may frequently experience gas, bloating, constipation, diarrhea, and abdominal pain. The purpose of...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962596/ https://www.ncbi.nlm.nih.gov/pubmed/35346230 http://dx.doi.org/10.1186/s12955-022-01956-4 |
_version_ | 1784677835936366592 |
---|---|
author | Beke, Matthew Burns, Alyssa M. Weir, Sydney Solch, Rebecca J. Judkins, Taylor C. Nieves, Carmelo Langkamp-Henken, Bobbi |
author_facet | Beke, Matthew Burns, Alyssa M. Weir, Sydney Solch, Rebecca J. Judkins, Taylor C. Nieves, Carmelo Langkamp-Henken, Bobbi |
author_sort | Beke, Matthew |
collection | PubMed |
description | BACKGROUND: Few health-related quality of life (QOL) questionnaires are designed specifically for healthy populations and are specific to gastrointestinal (GI) symptoms even though healthy individuals may frequently experience gas, bloating, constipation, diarrhea, and abdominal pain. The purpose of this study was to develop and validate a tool that could assess the impact of GI symptoms on digestion-associated QOL in otherwise healthy individuals. METHODS: After a review of current literature and with input from experienced GI researchers, a 24-item questionnaire was created. The questionnaire was reduced to 9 items with input from focus groups comprised of healthy adults experiencing GI-related symptoms and through variability analysis. The Digestion-associated QOL Questionnaire (DQLQ) was designed to be sensitive to the physical and mental well-being changes that may occur due to GI symptoms. The DQLQ was assessed for internal consistency reliability (Cronbach’s alpha; McDonald’s omega), test–retest reliability (intraclass correlation coefficient, ICC), and construct validity (Pearson correlations) in a study with healthy, academically stressed, undergraduate students. Convergent validity was evaluated by correlating the DQLQ with gastrointestinal symptom rating scale (GSRS) scores. Divergent validity was assessed by correlating DQLQ scores with stress scores, and bowel satisfaction scores. RESULTS: A total of 594 students (age 18–30 years) completed the DQLQ. Internal consistency reliability was favorable (n = 594; α = 0.84, ω = 0.84). A high level of agreement and correlation between DQLQ scores was found with the test–retest reliability analysis (n = 273; ICC = 0.89). The questionnaire was shown to have good convergent validity through correlation with the GSRS (n = 594; r = 0.54). Divergent validity was also shown to be appropriate by correlating DQLQ scores with stress (n = 592; r = 0.13, p < 0.005), and bowel satisfaction (n = 592; r = 0.18, p < 0.001) scores. CONCLUSION: The DQLQ is a reliable and valid questionnaire for assessing digestion-associated QOL in healthy individuals. |
format | Online Article Text |
id | pubmed-8962596 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-89625962022-03-30 Validation of a novel quality of life questionnaire: the Digestion-associated Quality of Life Questionnaire (DQLQ) Beke, Matthew Burns, Alyssa M. Weir, Sydney Solch, Rebecca J. Judkins, Taylor C. Nieves, Carmelo Langkamp-Henken, Bobbi Health Qual Life Outcomes Research BACKGROUND: Few health-related quality of life (QOL) questionnaires are designed specifically for healthy populations and are specific to gastrointestinal (GI) symptoms even though healthy individuals may frequently experience gas, bloating, constipation, diarrhea, and abdominal pain. The purpose of this study was to develop and validate a tool that could assess the impact of GI symptoms on digestion-associated QOL in otherwise healthy individuals. METHODS: After a review of current literature and with input from experienced GI researchers, a 24-item questionnaire was created. The questionnaire was reduced to 9 items with input from focus groups comprised of healthy adults experiencing GI-related symptoms and through variability analysis. The Digestion-associated QOL Questionnaire (DQLQ) was designed to be sensitive to the physical and mental well-being changes that may occur due to GI symptoms. The DQLQ was assessed for internal consistency reliability (Cronbach’s alpha; McDonald’s omega), test–retest reliability (intraclass correlation coefficient, ICC), and construct validity (Pearson correlations) in a study with healthy, academically stressed, undergraduate students. Convergent validity was evaluated by correlating the DQLQ with gastrointestinal symptom rating scale (GSRS) scores. Divergent validity was assessed by correlating DQLQ scores with stress scores, and bowel satisfaction scores. RESULTS: A total of 594 students (age 18–30 years) completed the DQLQ. Internal consistency reliability was favorable (n = 594; α = 0.84, ω = 0.84). A high level of agreement and correlation between DQLQ scores was found with the test–retest reliability analysis (n = 273; ICC = 0.89). The questionnaire was shown to have good convergent validity through correlation with the GSRS (n = 594; r = 0.54). Divergent validity was also shown to be appropriate by correlating DQLQ scores with stress (n = 592; r = 0.13, p < 0.005), and bowel satisfaction (n = 592; r = 0.18, p < 0.001) scores. CONCLUSION: The DQLQ is a reliable and valid questionnaire for assessing digestion-associated QOL in healthy individuals. BioMed Central 2022-03-28 /pmc/articles/PMC8962596/ /pubmed/35346230 http://dx.doi.org/10.1186/s12955-022-01956-4 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Beke, Matthew Burns, Alyssa M. Weir, Sydney Solch, Rebecca J. Judkins, Taylor C. Nieves, Carmelo Langkamp-Henken, Bobbi Validation of a novel quality of life questionnaire: the Digestion-associated Quality of Life Questionnaire (DQLQ) |
title | Validation of a novel quality of life questionnaire: the Digestion-associated Quality of Life Questionnaire (DQLQ) |
title_full | Validation of a novel quality of life questionnaire: the Digestion-associated Quality of Life Questionnaire (DQLQ) |
title_fullStr | Validation of a novel quality of life questionnaire: the Digestion-associated Quality of Life Questionnaire (DQLQ) |
title_full_unstemmed | Validation of a novel quality of life questionnaire: the Digestion-associated Quality of Life Questionnaire (DQLQ) |
title_short | Validation of a novel quality of life questionnaire: the Digestion-associated Quality of Life Questionnaire (DQLQ) |
title_sort | validation of a novel quality of life questionnaire: the digestion-associated quality of life questionnaire (dqlq) |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962596/ https://www.ncbi.nlm.nih.gov/pubmed/35346230 http://dx.doi.org/10.1186/s12955-022-01956-4 |
work_keys_str_mv | AT bekematthew validationofanovelqualityoflifequestionnairethedigestionassociatedqualityoflifequestionnairedqlq AT burnsalyssam validationofanovelqualityoflifequestionnairethedigestionassociatedqualityoflifequestionnairedqlq AT weirsydney validationofanovelqualityoflifequestionnairethedigestionassociatedqualityoflifequestionnairedqlq AT solchrebeccaj validationofanovelqualityoflifequestionnairethedigestionassociatedqualityoflifequestionnairedqlq AT judkinstaylorc validationofanovelqualityoflifequestionnairethedigestionassociatedqualityoflifequestionnairedqlq AT nievescarmelo validationofanovelqualityoflifequestionnairethedigestionassociatedqualityoflifequestionnairedqlq AT langkamphenkenbobbi validationofanovelqualityoflifequestionnairethedigestionassociatedqualityoflifequestionnairedqlq |