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Hypernatremia at a Tertiary Hospital Intensive Care Unit in South Africa
Background Hypernatremia in the critical care setting is a major cause of morbidity and mortality. However, data pertaining to this has not been evaluated in South African hospitals. The aim of this study was to evaluate hypernatremia with regards to its prevalence, associated factors, and outcomes...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962634/ https://www.ncbi.nlm.nih.gov/pubmed/35371787 http://dx.doi.org/10.7759/cureus.22648 |
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author | Mapata, Limbani Richards, Guy A Laher, Abdullah E |
author_facet | Mapata, Limbani Richards, Guy A Laher, Abdullah E |
author_sort | Mapata, Limbani |
collection | PubMed |
description | Background Hypernatremia in the critical care setting is a major cause of morbidity and mortality. However, data pertaining to this has not been evaluated in South African hospitals. The aim of this study was to evaluate hypernatremia with regards to its prevalence, associated factors, and outcomes at an academic hospital intensive care unit (ICU) in Johannesburg, South Africa. Methods The ICU charts of patients admitted to the Charlotte Maxeke Johannesburg Academic Hospital adult general ICU from June 1, 2016 to May 31, 2017 were retrospectively reviewed. Subjects were categorized into three groups namely, ICU-acquired hypernatremia (IAH), pre-admission hypernatremia (PAH), and normonatremia. Data was compared between the three groups. Results Of the 833 subjects that were enrolled, 310 (37.2%) were hypernatremic. IAH was present in 144 (17.2%) and PAH in 166 (19.9%) subjects. Hypernatremia was significantly (p <0.05) associated with a higher rate of altered mental status, higher Acute Physiologic Assessment and Chronic Health Evaluation II (APACHE II) scores, a higher rate and duration of mechanical ventilation, a greater need for inotropic/vasopressor support, longer ICU stay and higher ICU mortality. Conclusion Hypernatremia in ICU patients remains a significant contributor to morbidity, mortality, and ICU length of stay. The prevalence of hypernatremia was much higher than that reported in higher-income countries. |
format | Online Article Text |
id | pubmed-8962634 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-89626342022-04-01 Hypernatremia at a Tertiary Hospital Intensive Care Unit in South Africa Mapata, Limbani Richards, Guy A Laher, Abdullah E Cureus Emergency Medicine Background Hypernatremia in the critical care setting is a major cause of morbidity and mortality. However, data pertaining to this has not been evaluated in South African hospitals. The aim of this study was to evaluate hypernatremia with regards to its prevalence, associated factors, and outcomes at an academic hospital intensive care unit (ICU) in Johannesburg, South Africa. Methods The ICU charts of patients admitted to the Charlotte Maxeke Johannesburg Academic Hospital adult general ICU from June 1, 2016 to May 31, 2017 were retrospectively reviewed. Subjects were categorized into three groups namely, ICU-acquired hypernatremia (IAH), pre-admission hypernatremia (PAH), and normonatremia. Data was compared between the three groups. Results Of the 833 subjects that were enrolled, 310 (37.2%) were hypernatremic. IAH was present in 144 (17.2%) and PAH in 166 (19.9%) subjects. Hypernatremia was significantly (p <0.05) associated with a higher rate of altered mental status, higher Acute Physiologic Assessment and Chronic Health Evaluation II (APACHE II) scores, a higher rate and duration of mechanical ventilation, a greater need for inotropic/vasopressor support, longer ICU stay and higher ICU mortality. Conclusion Hypernatremia in ICU patients remains a significant contributor to morbidity, mortality, and ICU length of stay. The prevalence of hypernatremia was much higher than that reported in higher-income countries. Cureus 2022-02-27 /pmc/articles/PMC8962634/ /pubmed/35371787 http://dx.doi.org/10.7759/cureus.22648 Text en Copyright © 2022, Mapata et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Emergency Medicine Mapata, Limbani Richards, Guy A Laher, Abdullah E Hypernatremia at a Tertiary Hospital Intensive Care Unit in South Africa |
title | Hypernatremia at a Tertiary Hospital Intensive Care Unit in South Africa |
title_full | Hypernatremia at a Tertiary Hospital Intensive Care Unit in South Africa |
title_fullStr | Hypernatremia at a Tertiary Hospital Intensive Care Unit in South Africa |
title_full_unstemmed | Hypernatremia at a Tertiary Hospital Intensive Care Unit in South Africa |
title_short | Hypernatremia at a Tertiary Hospital Intensive Care Unit in South Africa |
title_sort | hypernatremia at a tertiary hospital intensive care unit in south africa |
topic | Emergency Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962634/ https://www.ncbi.nlm.nih.gov/pubmed/35371787 http://dx.doi.org/10.7759/cureus.22648 |
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