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Potential of PKM2 as a drug target in mouse models with type 1 diabetes mellitus

BACKGROUND: This study aimed to determine the effect of PKM2 knockout in STZ induced type 1 diabetes mellitus (T1D) mouse models and to explore the possible mechanism. METHOD: PKM2fl/fl C57BL/6 mouse was backcrossed with Ins‐1cre C57BL/6 mouse to generate β‐cell‐specific PKM2 knockout mouse after ta...

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Detalles Bibliográficos
Autores principales:	Liu, Junbin, Li, Zhixia, Huang, Gan, Zhou, Zhiguang, Zheng, Peilin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962638/ https://www.ncbi.nlm.nih.gov/pubmed/35349748 http://dx.doi.org/10.1002/iid3.593

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