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LRRK2 regulates actin assembly for spindle migration and mitochondrial function in mouse oocyte meiosis
Leucine-rich-repeat kinase 2 (LRRK2) belongs to the Roco GTPase family and is a large multidomain protein harboring both GTPase and kinase activities. LRRK2 plays indispensable roles in many processes, such as autophagy and vesicle trafficking in mitosis. In this study, we showed the critical roles...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962687/ https://www.ncbi.nlm.nih.gov/pubmed/34918122 http://dx.doi.org/10.1093/jmcb/mjab079 |