LRRK2 regulates actin assembly for spindle migration and mitochondrial function in mouse oocyte meiosis

Leucine-rich-repeat kinase 2 (LRRK2) belongs to the Roco GTPase family and is a large multidomain protein harboring both GTPase and kinase activities. LRRK2 plays indispensable roles in many processes, such as autophagy and vesicle trafficking in mitosis. In this study, we showed the critical roles...

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Detalles Bibliográficos
Autores principales: Pan, Zhen-Nan, Liu, Jing-Cai, Ju, Jia-Qian, Wang, Yue, Sun, Shao-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962687/
https://www.ncbi.nlm.nih.gov/pubmed/34918122
http://dx.doi.org/10.1093/jmcb/mjab079

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