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Maternal tobacco smoke exposure is associated with increased DNA methylation at human metastable epialleles in infant cord blood
Metastable epialleles (MEs) are genomic regions that are stochastically methylated prior to germ layer specification and exhibit high interindividual but low intra-individual variability across tissues. ME methylation is vulnerable to environmental stressors, including diet. Tobacco smoke (TS) expos...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962709/ https://www.ncbi.nlm.nih.gov/pubmed/35355955 http://dx.doi.org/10.1093/eep/dvac005 |