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Reassessing Reported Deaths and Estimated Infection Attack Rate during the First 6 Months of the COVID-19 Epidemic, Delhi, India
India reported >10 million coronavirus disease (COVID-19) cases and 149,000 deaths in 2020. To reassess reported deaths and estimate incidence rates during the first 6 months of the epidemic, we used a severe acute respiratory syndrome coronavirus 2 transmission model fit to data from 3 serosurve...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Centers for Disease Control and Prevention
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962916/ https://www.ncbi.nlm.nih.gov/pubmed/35213800 http://dx.doi.org/10.3201/eid2804.210879 |
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author | Pons-Salort, Margarita John, Jacob Watson, Oliver J. Brazeau, Nicholas F. Verity, Robert Kang, Gagandeep Grassly, Nicholas C. |
author_facet | Pons-Salort, Margarita John, Jacob Watson, Oliver J. Brazeau, Nicholas F. Verity, Robert Kang, Gagandeep Grassly, Nicholas C. |
author_sort | Pons-Salort, Margarita |
collection | PubMed |
description | India reported >10 million coronavirus disease (COVID-19) cases and 149,000 deaths in 2020. To reassess reported deaths and estimate incidence rates during the first 6 months of the epidemic, we used a severe acute respiratory syndrome coronavirus 2 transmission model fit to data from 3 serosurveys in Delhi and time-series documentation of reported deaths. We estimated 48.7% (95% credible interval 22.1%–76.8%) cumulative infection in the population through the end of September 2020. Using an age-adjusted overall infection fatality ratio based on age-specific estimates from mostly high-income countries, we estimated that just 15.0% (95% credible interval 9.3%–34.0%) of COVID-19 deaths had been reported, indicating either substantial underreporting or lower age-specific infection-fatality ratios in India than in high-income countries. Despite the estimated high attack rate, additional epidemic waves occurred in late 2020 and April–May 2021. Future dynamics will depend on the duration of natural and vaccine-induced immunity and their effectiveness against new variants. |
format | Online Article Text |
id | pubmed-8962916 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Centers for Disease Control and Prevention |
record_format | MEDLINE/PubMed |
spelling | pubmed-89629162022-04-02 Reassessing Reported Deaths and Estimated Infection Attack Rate during the First 6 Months of the COVID-19 Epidemic, Delhi, India Pons-Salort, Margarita John, Jacob Watson, Oliver J. Brazeau, Nicholas F. Verity, Robert Kang, Gagandeep Grassly, Nicholas C. Emerg Infect Dis Research India reported >10 million coronavirus disease (COVID-19) cases and 149,000 deaths in 2020. To reassess reported deaths and estimate incidence rates during the first 6 months of the epidemic, we used a severe acute respiratory syndrome coronavirus 2 transmission model fit to data from 3 serosurveys in Delhi and time-series documentation of reported deaths. We estimated 48.7% (95% credible interval 22.1%–76.8%) cumulative infection in the population through the end of September 2020. Using an age-adjusted overall infection fatality ratio based on age-specific estimates from mostly high-income countries, we estimated that just 15.0% (95% credible interval 9.3%–34.0%) of COVID-19 deaths had been reported, indicating either substantial underreporting or lower age-specific infection-fatality ratios in India than in high-income countries. Despite the estimated high attack rate, additional epidemic waves occurred in late 2020 and April–May 2021. Future dynamics will depend on the duration of natural and vaccine-induced immunity and their effectiveness against new variants. Centers for Disease Control and Prevention 2022-04 /pmc/articles/PMC8962916/ /pubmed/35213800 http://dx.doi.org/10.3201/eid2804.210879 Text en https://creativecommons.org/licenses/by/4.0/Emerging Infectious Diseases is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited. |
spellingShingle | Research Pons-Salort, Margarita John, Jacob Watson, Oliver J. Brazeau, Nicholas F. Verity, Robert Kang, Gagandeep Grassly, Nicholas C. Reassessing Reported Deaths and Estimated Infection Attack Rate during the First 6 Months of the COVID-19 Epidemic, Delhi, India |
title | Reassessing Reported Deaths and Estimated Infection Attack Rate during the First 6 Months of the COVID-19 Epidemic, Delhi, India |
title_full | Reassessing Reported Deaths and Estimated Infection Attack Rate during the First 6 Months of the COVID-19 Epidemic, Delhi, India |
title_fullStr | Reassessing Reported Deaths and Estimated Infection Attack Rate during the First 6 Months of the COVID-19 Epidemic, Delhi, India |
title_full_unstemmed | Reassessing Reported Deaths and Estimated Infection Attack Rate during the First 6 Months of the COVID-19 Epidemic, Delhi, India |
title_short | Reassessing Reported Deaths and Estimated Infection Attack Rate during the First 6 Months of the COVID-19 Epidemic, Delhi, India |
title_sort | reassessing reported deaths and estimated infection attack rate during the first 6 months of the covid-19 epidemic, delhi, india |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962916/ https://www.ncbi.nlm.nih.gov/pubmed/35213800 http://dx.doi.org/10.3201/eid2804.210879 |
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