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Alpelisib Plus Fulvestrant or Letrozole Demonstrates Sustained Benefits Across Subgroups of Patients with PIK3CA-Mutated HR+/HER2– Advanced Breast Cancer
Alpelisib and endocrine therapy provides ongoing treatment benefits for patients with HR-positive, HER2-negative, PIK3CA-mutated advanced breast cancer, according to updated findings from all 3 cohorts of the phase II BYLieve trial.
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963159/ https://www.ncbi.nlm.nih.gov/pubmed/35348782 http://dx.doi.org/10.1093/oncolo/oyac011 |
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author | Jacobson, Anne |
author_facet | Jacobson, Anne |
author_sort | Jacobson, Anne |
collection | PubMed |
description | Alpelisib and endocrine therapy provides ongoing treatment benefits for patients with HR-positive, HER2-negative, PIK3CA-mutated advanced breast cancer, according to updated findings from all 3 cohorts of the phase II BYLieve trial. |
format | Online Article Text |
id | pubmed-8963159 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-89631592022-03-29 Alpelisib Plus Fulvestrant or Letrozole Demonstrates Sustained Benefits Across Subgroups of Patients with PIK3CA-Mutated HR+/HER2– Advanced Breast Cancer Jacobson, Anne Oncologist Conference Perspectives: Highlights from SABCS Alpelisib and endocrine therapy provides ongoing treatment benefits for patients with HR-positive, HER2-negative, PIK3CA-mutated advanced breast cancer, according to updated findings from all 3 cohorts of the phase II BYLieve trial. Oxford University Press 2022-03-28 /pmc/articles/PMC8963159/ /pubmed/35348782 http://dx.doi.org/10.1093/oncolo/oyac011 Text en © The Author(s) 2022. Published by Oxford University Press. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Conference Perspectives: Highlights from SABCS Jacobson, Anne Alpelisib Plus Fulvestrant or Letrozole Demonstrates Sustained Benefits Across Subgroups of Patients with PIK3CA-Mutated HR+/HER2– Advanced Breast Cancer |
title | Alpelisib Plus Fulvestrant or Letrozole Demonstrates Sustained Benefits Across Subgroups of Patients with PIK3CA-Mutated HR+/HER2– Advanced Breast Cancer |
title_full | Alpelisib Plus Fulvestrant or Letrozole Demonstrates Sustained Benefits Across Subgroups of Patients with PIK3CA-Mutated HR+/HER2– Advanced Breast Cancer |
title_fullStr | Alpelisib Plus Fulvestrant or Letrozole Demonstrates Sustained Benefits Across Subgroups of Patients with PIK3CA-Mutated HR+/HER2– Advanced Breast Cancer |
title_full_unstemmed | Alpelisib Plus Fulvestrant or Letrozole Demonstrates Sustained Benefits Across Subgroups of Patients with PIK3CA-Mutated HR+/HER2– Advanced Breast Cancer |
title_short | Alpelisib Plus Fulvestrant or Letrozole Demonstrates Sustained Benefits Across Subgroups of Patients with PIK3CA-Mutated HR+/HER2– Advanced Breast Cancer |
title_sort | alpelisib plus fulvestrant or letrozole demonstrates sustained benefits across subgroups of patients with pik3ca-mutated hr+/her2– advanced breast cancer |
topic | Conference Perspectives: Highlights from SABCS |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963159/ https://www.ncbi.nlm.nih.gov/pubmed/35348782 http://dx.doi.org/10.1093/oncolo/oyac011 |
work_keys_str_mv | AT jacobsonanne alpelisibplusfulvestrantorletrozoledemonstratessustainedbenefitsacrosssubgroupsofpatientswithpik3camutatedhrher2advancedbreastcancer |