Natural Human Immunity Against Staphylococcal Protein A Relies on Effector Functions Triggered by IgG3

Staphylococcal protein A (SpA) is a multifunctional, highly conserved virulence factor of Staphylococcus aureus. By binding the Fc portion of all human IgG subclasses apart from IgG3, SpA interferes with antibody and complement deposition on the bacterial surface, impairing staphylococcal clearance...

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Detalles Bibliográficos
Autores principales: Boero, Elena, Cruz, Ana Rita, Pansegrau, Werner, Giovani, Cinzia, Rooijakkers, Suzan H. M., van Kessel, Kok P. M., van Strijp, Jos A. G., Bagnoli, Fabio, Manetti, Andrea G. O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963248/
https://www.ncbi.nlm.nih.gov/pubmed/35359919
http://dx.doi.org/10.3389/fimmu.2022.834711

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963248/
https://www.ncbi.nlm.nih.gov/pubmed/35359919
http://dx.doi.org/10.3389/fimmu.2022.834711

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