Thermometer: a webserver to predict protein thermal stability

MOTIVATION: Thermal properties of proteins are of great importance for a number of theoretical and practical implications. Predicting the thermal stability of a protein is a difficult and still scarcely addressed task. RESULTS: Here, we introduce Thermometer, a webserver to assess the thermal stabil...

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Detalles Bibliográficos
Autores principales: Miotto, Mattia, Armaos, Alexandros, Di Rienzo, Lorenzo, Ruocco, Giancarlo, Milanetti, Edoardo, Tartaglia, Gian Gaetano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Applications Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963285/
https://www.ncbi.nlm.nih.gov/pubmed/35020787
http://dx.doi.org/10.1093/bioinformatics/btab868
Descripción
Sumario:MOTIVATION: Thermal properties of proteins are of great importance for a number of theoretical and practical implications. Predicting the thermal stability of a protein is a difficult and still scarcely addressed task. RESULTS: Here, we introduce Thermometer, a webserver to assess the thermal stability of a protein using structural information. Thermometer is implemented as a publicly available, user-friendly interface. AVAILABILITY AND IMPLEMENTATION: Our server can be found at the following link (all major browser supported): http://service.tartaglialab.com/new_submission/thermometer_file. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.

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