Thermometer: a webserver to predict protein thermal stability

MOTIVATION: Thermal properties of proteins are of great importance for a number of theoretical and practical implications. Predicting the thermal stability of a protein is a difficult and still scarcely addressed task. RESULTS: Here, we introduce Thermometer, a webserver to assess the thermal stabil...

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Detalles Bibliográficos
Autores principales: Miotto, Mattia, Armaos, Alexandros, Di Rienzo, Lorenzo, Ruocco, Giancarlo, Milanetti, Edoardo, Tartaglia, Gian Gaetano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Applications Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963285/
https://www.ncbi.nlm.nih.gov/pubmed/35020787
http://dx.doi.org/10.1093/bioinformatics/btab868
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author Miotto, Mattia
Armaos, Alexandros
Di Rienzo, Lorenzo
Ruocco, Giancarlo
Milanetti, Edoardo
Tartaglia, Gian Gaetano
author_facet Miotto, Mattia
Armaos, Alexandros
Di Rienzo, Lorenzo
Ruocco, Giancarlo
Milanetti, Edoardo
Tartaglia, Gian Gaetano
author_sort Miotto, Mattia
collection PubMed
description MOTIVATION: Thermal properties of proteins are of great importance for a number of theoretical and practical implications. Predicting the thermal stability of a protein is a difficult and still scarcely addressed task. RESULTS: Here, we introduce Thermometer, a webserver to assess the thermal stability of a protein using structural information. Thermometer is implemented as a publicly available, user-friendly interface. AVAILABILITY AND IMPLEMENTATION: Our server can be found at the following link (all major browser supported): http://service.tartaglialab.com/new_submission/thermometer_file. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.
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spelling pubmed-89632852022-03-29 Thermometer: a webserver to predict protein thermal stability Miotto, Mattia Armaos, Alexandros Di Rienzo, Lorenzo Ruocco, Giancarlo Milanetti, Edoardo Tartaglia, Gian Gaetano Bioinformatics Applications Note MOTIVATION: Thermal properties of proteins are of great importance for a number of theoretical and practical implications. Predicting the thermal stability of a protein is a difficult and still scarcely addressed task. RESULTS: Here, we introduce Thermometer, a webserver to assess the thermal stability of a protein using structural information. Thermometer is implemented as a publicly available, user-friendly interface. AVAILABILITY AND IMPLEMENTATION: Our server can be found at the following link (all major browser supported): http://service.tartaglialab.com/new_submission/thermometer_file. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online. Oxford University Press 2022-01-10 /pmc/articles/PMC8963285/ /pubmed/35020787 http://dx.doi.org/10.1093/bioinformatics/btab868 Text en © The Author(s) 2022. Published by Oxford University Press. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Applications Note
Miotto, Mattia
Armaos, Alexandros
Di Rienzo, Lorenzo
Ruocco, Giancarlo
Milanetti, Edoardo
Tartaglia, Gian Gaetano
Thermometer: a webserver to predict protein thermal stability
title Thermometer: a webserver to predict protein thermal stability
title_full Thermometer: a webserver to predict protein thermal stability
title_fullStr Thermometer: a webserver to predict protein thermal stability
title_full_unstemmed Thermometer: a webserver to predict protein thermal stability
title_short Thermometer: a webserver to predict protein thermal stability
title_sort thermometer: a webserver to predict protein thermal stability
topic Applications Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963285/
https://www.ncbi.nlm.nih.gov/pubmed/35020787
http://dx.doi.org/10.1093/bioinformatics/btab868
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