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COVID-19 association with purpura fulminans: report of a life threatening complication in a fully vaccinated patient

SARS-CoV-2 manifestations have been an ongoing evolving topic that has spread beyond its initial respiratory associations. Recently, there have been reports of COVID-19 infections found to be associated with vascular pathologies. Here, we describe a case of a fully vaccinated COVID-19 adult male wit...

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Autores principales: Zhitny, Vladislav Pavlovich, Lyons, Mitchell, Perloff, Andrea, Menezes, John, Pistorio, Ashley, Baynosa, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963295/
https://www.ncbi.nlm.nih.gov/pubmed/35355577
http://dx.doi.org/10.1093/jscr/rjac095
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author Zhitny, Vladislav Pavlovich
Lyons, Mitchell
Perloff, Andrea
Menezes, John
Pistorio, Ashley
Baynosa, Richard
author_facet Zhitny, Vladislav Pavlovich
Lyons, Mitchell
Perloff, Andrea
Menezes, John
Pistorio, Ashley
Baynosa, Richard
author_sort Zhitny, Vladislav Pavlovich
collection PubMed
description SARS-CoV-2 manifestations have been an ongoing evolving topic that has spread beyond its initial respiratory associations. Recently, there have been reports of COVID-19 infections found to be associated with vascular pathologies. Here, we describe a case of a fully vaccinated COVID-19 adult male with past medical history of purpura fulminans that presented with diffuse necrotic cutaneous tissue sequelae resulting in intensive care unit management and dry gangrene of upper extremity. On admission, it was found that the patient had decreased activity rather than quantity of coagulation pathway protein S. Early recognition and work up are essential in patients with known history of vascular disease and confirmed cases of SARS-CoV-2 positive polymerase chain reaction.
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spelling pubmed-89632952022-03-29 COVID-19 association with purpura fulminans: report of a life threatening complication in a fully vaccinated patient Zhitny, Vladislav Pavlovich Lyons, Mitchell Perloff, Andrea Menezes, John Pistorio, Ashley Baynosa, Richard J Surg Case Rep Case Report SARS-CoV-2 manifestations have been an ongoing evolving topic that has spread beyond its initial respiratory associations. Recently, there have been reports of COVID-19 infections found to be associated with vascular pathologies. Here, we describe a case of a fully vaccinated COVID-19 adult male with past medical history of purpura fulminans that presented with diffuse necrotic cutaneous tissue sequelae resulting in intensive care unit management and dry gangrene of upper extremity. On admission, it was found that the patient had decreased activity rather than quantity of coagulation pathway protein S. Early recognition and work up are essential in patients with known history of vascular disease and confirmed cases of SARS-CoV-2 positive polymerase chain reaction. Oxford University Press 2022-03-26 /pmc/articles/PMC8963295/ /pubmed/35355577 http://dx.doi.org/10.1093/jscr/rjac095 Text en Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2022. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Zhitny, Vladislav Pavlovich
Lyons, Mitchell
Perloff, Andrea
Menezes, John
Pistorio, Ashley
Baynosa, Richard
COVID-19 association with purpura fulminans: report of a life threatening complication in a fully vaccinated patient
title COVID-19 association with purpura fulminans: report of a life threatening complication in a fully vaccinated patient
title_full COVID-19 association with purpura fulminans: report of a life threatening complication in a fully vaccinated patient
title_fullStr COVID-19 association with purpura fulminans: report of a life threatening complication in a fully vaccinated patient
title_full_unstemmed COVID-19 association with purpura fulminans: report of a life threatening complication in a fully vaccinated patient
title_short COVID-19 association with purpura fulminans: report of a life threatening complication in a fully vaccinated patient
title_sort covid-19 association with purpura fulminans: report of a life threatening complication in a fully vaccinated patient
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963295/
https://www.ncbi.nlm.nih.gov/pubmed/35355577
http://dx.doi.org/10.1093/jscr/rjac095
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