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COVID-19 association with purpura fulminans: report of a life threatening complication in a fully vaccinated patient
SARS-CoV-2 manifestations have been an ongoing evolving topic that has spread beyond its initial respiratory associations. Recently, there have been reports of COVID-19 infections found to be associated with vascular pathologies. Here, we describe a case of a fully vaccinated COVID-19 adult male wit...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963295/ https://www.ncbi.nlm.nih.gov/pubmed/35355577 http://dx.doi.org/10.1093/jscr/rjac095 |
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author | Zhitny, Vladislav Pavlovich Lyons, Mitchell Perloff, Andrea Menezes, John Pistorio, Ashley Baynosa, Richard |
author_facet | Zhitny, Vladislav Pavlovich Lyons, Mitchell Perloff, Andrea Menezes, John Pistorio, Ashley Baynosa, Richard |
author_sort | Zhitny, Vladislav Pavlovich |
collection | PubMed |
description | SARS-CoV-2 manifestations have been an ongoing evolving topic that has spread beyond its initial respiratory associations. Recently, there have been reports of COVID-19 infections found to be associated with vascular pathologies. Here, we describe a case of a fully vaccinated COVID-19 adult male with past medical history of purpura fulminans that presented with diffuse necrotic cutaneous tissue sequelae resulting in intensive care unit management and dry gangrene of upper extremity. On admission, it was found that the patient had decreased activity rather than quantity of coagulation pathway protein S. Early recognition and work up are essential in patients with known history of vascular disease and confirmed cases of SARS-CoV-2 positive polymerase chain reaction. |
format | Online Article Text |
id | pubmed-8963295 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-89632952022-03-29 COVID-19 association with purpura fulminans: report of a life threatening complication in a fully vaccinated patient Zhitny, Vladislav Pavlovich Lyons, Mitchell Perloff, Andrea Menezes, John Pistorio, Ashley Baynosa, Richard J Surg Case Rep Case Report SARS-CoV-2 manifestations have been an ongoing evolving topic that has spread beyond its initial respiratory associations. Recently, there have been reports of COVID-19 infections found to be associated with vascular pathologies. Here, we describe a case of a fully vaccinated COVID-19 adult male with past medical history of purpura fulminans that presented with diffuse necrotic cutaneous tissue sequelae resulting in intensive care unit management and dry gangrene of upper extremity. On admission, it was found that the patient had decreased activity rather than quantity of coagulation pathway protein S. Early recognition and work up are essential in patients with known history of vascular disease and confirmed cases of SARS-CoV-2 positive polymerase chain reaction. Oxford University Press 2022-03-26 /pmc/articles/PMC8963295/ /pubmed/35355577 http://dx.doi.org/10.1093/jscr/rjac095 Text en Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2022. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Zhitny, Vladislav Pavlovich Lyons, Mitchell Perloff, Andrea Menezes, John Pistorio, Ashley Baynosa, Richard COVID-19 association with purpura fulminans: report of a life threatening complication in a fully vaccinated patient |
title | COVID-19 association with purpura fulminans: report of a life threatening complication in a fully vaccinated patient |
title_full | COVID-19 association with purpura fulminans: report of a life threatening complication in a fully vaccinated patient |
title_fullStr | COVID-19 association with purpura fulminans: report of a life threatening complication in a fully vaccinated patient |
title_full_unstemmed | COVID-19 association with purpura fulminans: report of a life threatening complication in a fully vaccinated patient |
title_short | COVID-19 association with purpura fulminans: report of a life threatening complication in a fully vaccinated patient |
title_sort | covid-19 association with purpura fulminans: report of a life threatening complication in a fully vaccinated patient |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963295/ https://www.ncbi.nlm.nih.gov/pubmed/35355577 http://dx.doi.org/10.1093/jscr/rjac095 |
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