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Alterations of the miR-126-3p/POU2AF1/Spi-B Axis and JCPyV Reactivation in Multiple Sclerosis Patients Receiving Natalizumab

Natalizumab (NTZ) can reactivate human polyomavirus John Cunningham polyomavirus (JCPyV) latent infection and lead to progressive multifocal leukoencephalopathy (PML). NTZ modulates the expression of microRNA-126-3p (miR-126-3p) and its target genes, Spi-B, POU2AF1, and vascular cell adhesion molecu...

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Detalles Bibliográficos
Autores principales:	Mancuso, Roberta, Agostini, Simone, Hernis, Ambra, Caputo, Domenico, Galimberti, Daniela, Scarpini, Elio, Clerici, Mario
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Neurology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963350/ https://www.ncbi.nlm.nih.gov/pubmed/35359635 http://dx.doi.org/10.3389/fneur.2022.819911

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