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The Ameliorative Effect of JNK Inhibitor D-JNKI-1 on Neomycin-Induced Apoptosis in HEI-OC1 Cells

Aminoglycosides can cause ototoxicity and lead to hair cell damage. Neomycin-induced ototoxicity is related to increased production of reactive oxygen species (ROS) and triggering hair cell apoptosis. The c-Jun-N-terminal kinase (JNK) pathway plays an essential role during hair cell damage. This stu...

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Detalles Bibliográficos
Autores principales:	Zhao, Junling, Liu, Hao, Huang, Zhiwei, Yang, Ruiming, Gong, Liang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Molecular Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963355/ https://www.ncbi.nlm.nih.gov/pubmed/35359571 http://dx.doi.org/10.3389/fnmol.2022.824762

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