Improved cognition impairment by activating cannabinoid receptor type 2: Modulating CREB/BDNF expression and impeding TLR-4/NFκBp65/M1 microglia signaling pathway in D-galactose-injected ovariectomized rats

Alzheimer’s disease (AD) is characterized by an active inflammatory response induced by the brain’s deposition and accumulation of amyloid-beta (Aβ). Cannabinoid receptor type 2 (CB2R) is expressed in specific brain areas, modulating functions, and pathophysiologies in CNS. Herein, we aimed to evalu...

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Detalles Bibliográficos
Autores principales: Abd El-Rahman, Sahar S., Fayed, Hany M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963558/
https://www.ncbi.nlm.nih.gov/pubmed/35349580
http://dx.doi.org/10.1371/journal.pone.0265961

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963558/
https://www.ncbi.nlm.nih.gov/pubmed/35349580
http://dx.doi.org/10.1371/journal.pone.0265961

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