Cargando…

Improved cognition impairment by activating cannabinoid receptor type 2: Modulating CREB/BDNF expression and impeding TLR-4/NFκBp65/M1 microglia signaling pathway in D-galactose-injected ovariectomized rats

Alzheimer’s disease (AD) is characterized by an active inflammatory response induced by the brain’s deposition and accumulation of amyloid-beta (Aβ). Cannabinoid receptor type 2 (CB2R) is expressed in specific brain areas, modulating functions, and pathophysiologies in CNS. Herein, we aimed to evalu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Abd El-Rahman, Sahar S., Fayed, Hany M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963558/ https://www.ncbi.nlm.nih.gov/pubmed/35349580 http://dx.doi.org/10.1371/journal.pone.0265961

Ejemplares similares

Serum NF-κBp65, TLR4 as Biomarker for Diagnosis of Preeclampsia
por: Litang, Zhao, et al.
Publicado: (2017)

Cynomorium songaricum Extract Alleviates Memory Impairment through Increasing CREB/BDNF via Suppression of p38MAPK/ERK Pathway in Ovariectomized Rats
por: Tian, Fang-ze, et al.
Publicado: (2019)

Resveratrol mitigates lipopolysaccharide-mediated acute inflammation in rats by inhibiting the TLR4/NF-κBp65/MAPKs signaling cascade
por: Wang, Guangxi, et al.
Publicado: (2017)

Baicalin Inhibits Inflammation in Rats with Chronic Obstructive Pulmonary Disease by the TLR2/MYD88/NF-κBp65 Signaling Pathway
por: Ju, Jiangang, et al.
Publicado: (2022)

Antidepressant effects of aqueous extract of saffron and its effects on CREB, P-CREB, BDNF, and VGF proteins in rat cerebellum
por: Asrari, Najmeh, et al.
Publicado: (2018)

Brain-Derived Neurotrophic Factor (BDNF) Role in Cannabinoid-Mediated Neurogenesis
por: Ferreira, Filipa Fiel, et al.
Publicado: (2018)

Administration of Phytoceramide Enhances Memory and Upregulates the Expression of pCREB and BDNF in Hippocampus of Mice
por: Lee, Yeonju, et al.
Publicado: (2013)

PKA-CREB-BDNF signaling regulated long lasting antidepressant activities of Yueju but not ketamine
por: Xue, Wenda, et al.
Publicado: (2016)

Theobromine Improves Working Memory by Activating the CaMKII/CREB/BDNF Pathway in Rats
por: Islam, Rafiad, et al.
Publicado: (2019)

Dietary Flavonoids Interaction with CREB-BDNF Pathway: An  Unconventional Approach for Comprehensive Management of Epilepsy
por: Sharma, Pallavi, et al.
Publicado: (2019)

Roflumilast Ameliorates Isoflurane-Induced Inflammation in Astrocytes via the CREB/BDNF Signaling Pathway
por: Zhang, Chunyuan, et al.
Publicado: (2021)

Hesperidin Interacts With CREB-BDNF Signaling Pathway to Suppress Pentylenetetrazole-Induced Convulsions in Zebrafish
por: Sharma, Pallavi, et al.
Publicado: (2021)

Microglia Impede Oligodendrocyte Generation in Aged Brain
por: Luan, Weimin, et al.
Publicado: (2021)

Dapagliflozin as an autophagic enhancer via LKB1/AMPK/SIRT1 pathway in ovariectomized/d-galactose Alzheimer’s rat model
por: Ibrahim, Weam W., et al.
Publicado: (2022)

Microglia Control Neuronal Network Excitability via BDNF Signalling
por: Ferrini, Francesco, et al.
Publicado: (2013)

Glucocorticoid receptors recruit the CaMKIIα, BDNF–CREB pathways to mediate memory consolidation
por: Chen, Dillon Y., et al.
Publicado: (2012)

Exercise Prevents Memory Impairment Induced by Arsenic Exposure in Mice: Implication of Hippocampal BDNF and CREB
por: Sun, Bao-Fei, et al.
Publicado: (2015)

Inhibition of Necroptosis Rescues SAH-Induced Synaptic Impairments in Hippocampus via CREB-BDNF Pathway
por: Yang, Chunlei, et al.
Publicado: (2019)

Anti-depressant effects of oil from fructus gardeniae via PKA-CREB-BDNF signaling
por: Ruan, Jie, et al.
Publicado: (2019)

Xingnao Jieyu Decoction Ameliorates Poststroke Depression through the BDNF/ERK/CREB Pathway in Rats
por: Li, Tao, et al.
Publicado: (2018)

Knockdown of miR-124 Reduces Depression-like Behavior by Targeting CREB1 and BDNF
por: Yang, Wei, et al.
Publicado: (2020)

Sodium butyrate prevents radiation-induced cognitive impairment by restoring pCREB/BDNF expression
por: Lee, Hae June, et al.
Publicado: (2019)

Effect of vitamin D supplementation on CREB-TrkB-BDNF pathway in the hippocampus of diabetic rats
por: Nadimi, Hoda, et al.
Publicado: (2020)

Retraction of “Roflumilast Ameliorates Isoflurane-Induced Inflammation in Astrocytes via the CREB/BDNF Signaling Pathway”
por: Zhang, Chunyuan, et al.
Publicado: (2021)

Microglial ERK-NRBP1-CREB-BDNF signaling in sustained antidepressant actions of (R)-ketamine
por: Yao, Wei, et al.
Publicado: (2021)

Cannabinoids in Chronic Pain: Therapeutic Potential Through Microglia Modulation
por: van den Hoogen, Nynke J., et al.
Publicado: (2022)

An estradiol-independent BDNF-NPY cascade is involved in the antidepressant effect of mechanical acupuncture instruments in ovariectomized rats
por: Seo, Su Yeon, et al.
Publicado: (2018)

Melatonin Blocks Morphine-Induced Place Preference: Involvement of GLT-1, NF-κB, BDNF, and CREB in the Nucleus Accumbens
por: Alghamdi, Badrah S., et al.
Publicado: (2021)

Escitalopram Ameliorates Cognitive Impairment in D-Galactose-Injected Ovariectomized Rats: Modulation of JNK, GSK-3β, and ERK Signalling Pathways
por: Ibrahim, Weam W., et al.
Publicado: (2019)

Memantine/Aripiprazole Combination Alleviates Cognitive Dysfunction in Valproic Acid Rat Model of Autism: Hippocampal CREB/BDNF Signaling and Glutamate Homeostasis
por: Zohny, Sohir M., et al.
Publicado: (2023)

Antidepressant effects of crocin and its effects on transcript and protein levels of CREB, BDNF, and VGF in rat hippocampus
por: Vahdati Hassani, Faezeh, et al.
Publicado: (2014)

Study of the Role of CREB, BDNF, and VGF Neuropeptide in Long Term Antidepressant Activity of Crocin in the Rat Cerebellum
por: Razavi, Bibi Marjan, et al.
Publicado: (2017)

Long-term Administration of Salicylate-induced Changes in BDNF Expression and CREB Phosphorylation in the Auditory Cortex of Rats
por: Yi, Bin, et al.
Publicado: (2018)

Activation of ERK/CREB/BDNF pathway involved in abnormal behavior of neonatally Borna virus-infected rats
por: Li, Chenmeng, et al.
Publicado: (2018)

Correction: Microglial ERK-NRBP1-CREB-BDNF signaling in sustained antidepressant actions of (R)-ketamine
por: Yao, Wei, et al.
Publicado: (2021)

Long-term supplementation of dehydroepiandrosterone improved depressive-like behaviors by increasing BDNF expression in the hippocampus in ovariectomized rats
por: Wu, Siyang, et al.
Publicado: (2020)

Echinacoside exerts antidepressant-like effects through enhancing BDNF-CREB pathway and inhibiting neuroinflammation via regulating microglia M1/M2 polarization and JAK1/STAT3 pathway
por: Lu, Renrui, et al.
Publicado: (2023)

Osthole Alleviates D-Galactose-Induced Liver Injury In Vivo via the TLR4/MAPK/NF-κB Pathways
por: Ma, Zhe, et al.
Publicado: (2023)

Reversion of BDNF, Akt and CREB in Hippocampus of Chronic Unpredictable Stress Induced Rats: Effects of Phytochemical, Bacopa Monnieri
por: Hazra, Somoday, et al.
Publicado: (2017)

Crocin Acting as a Neuroprotective Agent against Methamphetamine-induced Neurodegeneration via CREB-BDNF Signaling Pathway
por: Mozaffari, Shiva, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_48v9k54ks6bd9i6b3djmbr09m9