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Identification of gingerenone A as a novel senolytic compound
Senescent cells accumulate with aging and have been shown to contribute to age-associated diseases and organ dysfunction. Eliminating senescent cells with senolytic drugs has been shown to improve age phenotypes in mouse models and there is some initial evidence that it may improve the health of per...
Autores principales: | Moaddel, Ruin, Rossi, Martina, Rodriguez, Stephanie, Munk, Rachel, Khadeer, Mohammed, Abdelmohsen, Kotb, Gorospe, Myriam, Ferrucci, Luigi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963586/ https://www.ncbi.nlm.nih.gov/pubmed/35349590 http://dx.doi.org/10.1371/journal.pone.0266135 |
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