Targeting the Retinoid X Receptor Pathway Prevents and Ameliorates Murine Chronic Graft-Versus-Host Disease

Most allogeneic hematopoietic stem cell transplant (allo-HSCT) recipients receive peripheral blood stem cell grafts resulting in a 30%–70% incidence of chronic graft-versus-host disease (cGVHD), a major cause of mortality and morbidity in long-term survivors. While systemic steroids remain the stand...

Descripción completa

Detalles Bibliográficos
Autores principales: Thangavelu, Govindarajan, Zaiken, Michael C., Mohamed, Fathima A., Flynn, Ryan, Du, Jing, Rhee, Stephanie Y., Riddle, Megan J., Aguilar, Ethan G., Panoskaltsis-Mortari, Angela, Sanders, Martin E., Blazar, Bruce R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963714/
https://www.ncbi.nlm.nih.gov/pubmed/35359939
http://dx.doi.org/10.3389/fimmu.2022.765319

Ejemplares similares

Ejemplares similares