Thioredoxin overexpression in mitochondria showed minimum effects on aging and age-related diseases in male C57BL/6 mice

OBJECTIVE: In this study, the effects of overexpression of thioredoxin 2 (Trx2) on aging and age-related diseases were examined using Trx2 transgenic mice [Tg(TXN2](+/0)]. Because our previous studies demonstrated that thioredoxin (Trx) overexpression in the cytosol (Trx1) did not extend maximum lif...

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Detalles Bibliográficos
Autores principales: Roman, Madeline G., Flores, Lisa C., Cunningham, Geneva M., Cheng, Christie, Dube, Sara, Allen, Colton, Van Remmen, Holly, Bai, Yidong, Hubbard, Gene B., Saunders, Thomas L., Ikeno, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963792/
https://www.ncbi.nlm.nih.gov/pubmed/35356005
http://dx.doi.org/10.31491/apt.2020.03.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963792/
https://www.ncbi.nlm.nih.gov/pubmed/35356005
http://dx.doi.org/10.31491/apt.2020.03.009

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