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Gene Expression-Based Signature Can Predict Sorafenib Response in Kidney Cancer

Sorafenib is a tyrosine kinase inhibitory drug with multiple molecular specificities that is approved for clinical use in second-line treatments of metastatic and advanced renal cell carcinomas (RCCs). However, only 10–40% of RCC patients respond on sorafenib-containing therapies, and personalizatio...

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Detalles Bibliográficos
Autores principales:	Gudkov, Alexander, Shirokorad, Valery, Kashintsev, Kirill, Sokov, Dmitriy, Nikitin, Daniil, Anisenko, Andrey, Borisov, Nicolas, Sekacheva, Marina, Gaifullin, Nurshat, Garazha, Andrew, Suntsova, Maria, Koroleva, Elena, Buzdin, Anton, Sorokin, Maksim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963850/ https://www.ncbi.nlm.nih.gov/pubmed/35359606 http://dx.doi.org/10.3389/fmolb.2022.753318

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