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Structural basis of dynamic P5CS filaments

The bifunctional enzyme Δ(1)-pyrroline-5-carboxylate synthase (P5CS) is vital to the synthesis of proline and ornithine, playing an essential role in human health and agriculture. Pathogenic mutations in the P5CS gene (ALDH18A1) lead to neurocutaneous syndrome and skin relaxation connective tissue d...

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Detalles Bibliográficos
Autores principales:	Zhong, Jiale, Guo, Chen-Jun, Zhou, Xian, Chang, Chia-Chun, Yin, Boqi, Zhang, Tianyi, Hu, Huan-Huan, Lu, Guang-Ming, Liu, Ji-Long
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2022
Materias:	Structural Biology and Molecular Biophysics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963878/ https://www.ncbi.nlm.nih.gov/pubmed/35286254 http://dx.doi.org/10.7554/eLife.76107

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