Cargando…

Degenerative Nucleus Pulposus Cells Derived Exosomes Promoted Cartilage Endplate Cells Apoptosis and Aggravated Intervertebral Disc Degeneration

Intervertebral disc (IVD) degeneration is a complex multifactorial disease model, which pathogenesis has not been fully defined. There are few studies on the information interaction between nucleus pulposus (NP) cells and cartilage endplate (CEP) cells. Exosomes, as a carrier of information communic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Feng, Xiaofei, Li, Yongchao, Su, Qihang, Tan, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963919/ https://www.ncbi.nlm.nih.gov/pubmed/35359595 http://dx.doi.org/10.3389/fmolb.2022.835976

Ejemplares similares

Cartilage endplate stem cells inhibit intervertebral disc degeneration by releasing exosomes to nucleus pulposus cells to activate Akt/autophagy
por: Luo, Liwen, et al.
Publicado: (2021)

Exosomes Secreted by Nucleus Pulposus Stem Cells Derived From Degenerative Intervertebral Disc Exacerbate Annulus Fibrosus Cell Degradation via Let-7b-5p
por: Zhuang, Yin, et al.
Publicado: (2022)

The role of endplate injury in intervertebral disc degeneration after vertebral augmentation in OVCF patients
por: Li, Yongchao, et al.
Publicado: (2023)

Cartilage Endplate Stem Cells Transdifferentiate Into Nucleus Pulposus Cells via Autocrine Exosomes
por: Luo, Liwen, et al.
Publicado: (2021)

Increased Expression of Prolyl Endopeptidase Induced by Oxidative Stress in Nucleus Pulposus Cells Aggravates Intervertebral Disc Degeneration
por: Zheng, Huo-Liang, et al.
Publicado: (2022)

Exhaustion of nucleus pulposus progenitor cells with ageing and degeneration of the intervertebral disc
por: Sakai, Daisuke, et al.
Publicado: (2012)

Circular RNAs in nucleus pulposus cell function and intervertebral disc degeneration
por: Li, Zheng, et al.
Publicado: (2019)

Characteristics of Stem Cells Derived from the Degenerated Human Intervertebral Disc Cartilage Endplate
por: Liu, Lan-Tao, et al.
Publicado: (2011)

Natural Products of Pharmacology and Mechanisms in Nucleus Pulposus Cells and Intervertebral Disc Degeneration
por: Chen, Hai-Wei, et al.
Publicado: (2021)

Effects of puerarin on the intervertebral disc degeneration and biological characteristics of nucleus pulposus cells
por: Tang, Hengtao, et al.
Publicado: (2022)

Psoralen synergizes with exosome-loaded SPC25 to alleviate senescence of nucleus pulposus cells in intervertebral disc degeneration
por: Yang, Lei, et al.
Publicado: (2023)

Injectable cartilage matrix hydrogel loaded with cartilage endplate stem cells engineered to release exosomes for non-invasive treatment of intervertebral disc degeneration
por: Luo, Liwen, et al.
Publicado: (2021)

Degenerated nucleus pulposus cells derived exosome carrying miR-27a-3p aggravates intervertebral disc degeneration by inducing M1 polarization of macrophages
por: Zhao, Xin, et al.
Publicado: (2023)

Autologous fibroblasts induce fibrosis of the nucleus pulposus to maintain the stability of degenerative intervertebral discs
por: Chen, Chen, et al.
Publicado: (2020)

Carbohydrate sulfotransferase 3 (CHST3) overexpression promotes cartilage endplate‐derived stem cells (CESCs) to regulate molecular mechanisms related to repair of intervertebral disc degeneration by rat nucleus pulposus
por: Guan, Yunzhi, et al.
Publicado: (2021)

Expression of ANGPTL4 in Nucleus Pulposus Tissues Is Associated with Intervertebral Disc Degeneration
por: Liu, Fan-jie, et al.
Publicado: (2021)

PLK1 Mitigates Intervertebral Disc Degeneration by Delaying Senescence of Nucleus Pulposus Cells
por: Zhang, Zhenlei, et al.
Publicado: (2022)

The Upregulation of COX2 in Human Degenerated Nucleus Pulposus: The Association of Inflammation with Intervertebral Disc Degeneration
por: Liu, Chang, et al.
Publicado: (2021)

Small Extracellular Vesicles Derived from Adipocytes Attenuate Intervertebral Disc Degeneration in Rats by Rejuvenating Senescent Nucleus Pulposus Cells and Endplate Cells by Delivering Exogenous NAMPT
por: Sun, Yongjin, et al.
Publicado: (2021)

Mesenchymal stem cells deliver exogenous miR‐21 via exosomes to inhibit nucleus pulposus cell apoptosis and reduce intervertebral disc degeneration
por: Cheng, Xiaofei, et al.
Publicado: (2017)

BMSC-Derived Exosomes Alleviate Intervertebral Disc Degeneration by Modulating AKT/mTOR-Mediated Autophagy of Nucleus Pulposus Cells
por: Xiao, Quan, et al.
Publicado: (2022)

Injectable hydrogel with nucleus pulposus-matched viscoelastic property prevents intervertebral disc degeneration
por: Jia, Haoruo, et al.
Publicado: (2022)

Discovery and Application of Postnatal Nucleus Pulposus Progenitors Essential for Intervertebral Disc Homeostasis and Degeneration
por: Gao, Bo, et al.
Publicado: (2022)

The cytokine and chemokine expression profile of nucleus pulposus cells: implications for degeneration and regeneration of the intervertebral disc
por: Phillips, Kate L E, et al.
Publicado: (2013)

Effect of optimized collagenase digestion on isolated and cultured nucleus pulposus cells in degenerated intervertebral discs
por: Feng, Xu, et al.
Publicado: (2018)

Apigenin Alleviates Intervertebral Disc Degeneration via Restoring Autophagy Flux in Nucleus Pulposus Cells
por: Xie, Chenglong, et al.
Publicado: (2022)

NF‐κB signalling pathways in nucleus pulposus cell function and intervertebral disc degeneration
por: Zhang, Guang‐Zhi, et al.
Publicado: (2021)

Overloaded axial stress activates the Wnt/β-Catenin pathway in nucleus pulposus cells of adult degenerative scoliosis combined with intervertebral disc degeneration
por: Cai, Zhijun, et al.
Publicado: (2023)

Expression of cartilage-derived morphogenetic protein in human intervertebral discs and its effect on matrix synthesis in degenerate human nucleus pulposus cells
por: Le Maitre, Christine L, et al.
Publicado: (2009)

Senescence of Nucleus Pulposus Chondrocytes in Human Intervertebral Discs
por: Kim, Ki-Won, et al.
Publicado: (2008)

Proteomic Signature of Nucleus Pulposus in Fetal Intervertebral Disc
por: Rajasekaran, Shanmuganathan, et al.
Publicado: (2020)

Injectable Hydrogel Combined with Nucleus Pulposus-Derived Mesenchymal Stem Cells for the Treatment of Degenerative Intervertebral Disc in Rats
por: Wang, Feng, et al.
Publicado: (2019)

Transplantation of allogenic nucleus pulposus cells attenuates intervertebral disc degeneration by inhibiting apoptosis and increasing migration
por: Wang, Weiheng, et al.
Publicado: (2018)

Effect of optimized collagenase digestion on isolated and cultured nucleus pulposus cells in degenerated intervertebral discs: Erratum
Publicado: (2018)

Effect of optimized collagenase digestion on isolated and cultured nucleus pulposus cells in degenerated intervertebral discs: Erratum
Publicado: (2019)

Upregulated lnc-HRK-2:1 prompts nucleus pulposus cell senescence in intervertebral disc degeneration
por: Liang, Dongbo, et al.
Publicado: (2020)

Acacetin Alleviates Inflammation and Matrix Degradation in Nucleus Pulposus Cells and Ameliorates Intervertebral Disc Degeneration in vivo
por: Wang, Hao, et al.
Publicado: (2020)

Mechanism of Long Noncoding RNA HOTAIR in Nucleus Pulposus Cell Autophagy and Apoptosis in Intervertebral Disc Degeneration
por: Zhang, Shujun, et al.
Publicado: (2022)

Single-Cell RNA Sequencing of the Nucleus Pulposus Reveals Chondrocyte Differentiation and Regulation in Intervertebral Disc Degeneration
por: Han, Shuo, et al.
Publicado: (2022)

Lactotransferrin promotes intervertebral disc degeneration by regulating Fas and inhibiting human nucleus pulposus cell apoptosis
por: Zhang, Xiao-Bo, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_fa5t1qid7prk33kpi6lr8jfc13