Selective Retinoic Acid Receptor γ Antagonist 7C is a Potent Enhancer of BMP-Induced Ectopic Endochondral Bone Formation

Bone morphogenetic proteins (BMPs) have been clinically applied for induction of bone formation in musculoskeletal disorders such as critical-sized bone defects, nonunions, and spinal fusion surgeries. However, the use of supraphysiological doses of BMP caused adverse events, which were sometimes li...

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Detalles Bibliográficos
Autores principales: Tateiwa, Daisuke, Kaito, Takashi, Hashimoto, Kunihiko, Okada, Rintaro, Kodama, Joe, Kushioka, Junichi, Bal, Zeynep, Tsukazaki, Hiroyuki, Nakagawa, Shinichi, Ukon, Yuichiro, Hirai, Hiromasa, Tian, Hongying, Alferiev, Ivan, Chorny, Michael, Otsuru, Satoru, Okada, Seiji, Iwamoto, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963923/
https://www.ncbi.nlm.nih.gov/pubmed/35359440
http://dx.doi.org/10.3389/fcell.2022.802699

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