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IL25 Enhanced Colitis-Associated Tumorigenesis in Mice by Upregulating Transcription Factor GLI1

Interleukin-25 (IL17E/IL25) plays a critical role in colitis and intestinal homeostasis. However, the expression and biological role of IL25 in colorectal cancer is not properly understood. In this study, we show that IL25 is mainly expressed by cancer stem cells in the colorectal cancer microenviro...

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Detalles Bibliográficos
Autores principales:	Liu, Junxi, Qian, Bingxiu, Zhou, Lin, Shen, Gang, Tan, Yandan, Liu, Siqi, Zhao, Zewei, Shi, Jianglin, Qi, Weiwei, Zhou, Ti, Yang, Xia, Gao, Guoquan, Yang, Zhonghan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963976/ https://www.ncbi.nlm.nih.gov/pubmed/35359953 http://dx.doi.org/10.3389/fimmu.2022.837262

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