Inhibition of SARS-CoV-2 replication in the lung with siRNA/VIPER polyplexes

SARS-CoV-2 has been the cause of a global pandemic since 2019 and remains a medical urgency. siRNA-based therapies are a promising strategy to fight viral infections. By targeting a specific region of the viral genome, siRNAs can efficiently downregulate viral replication and suppress viral infectio...

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Detalles Bibliográficos
Autores principales: Baldassi, Domizia, Ambike, Shubhankar, Feuerherd, Martin, Cheng, Cho-Chin, Peeler, David J., Feldmann, Daniel P., Porras-Gonzalez, Diana Leidy, Wei, Xin, Keller, Lea-Adriana, Kneidinger, Nikolaus, Stoleriu, Mircea Gabriel, Popp, Andreas, Burgstaller, Gerald, Pun, Suzie H., Michler, Thomas, Merkel, Olivia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8963978/
https://www.ncbi.nlm.nih.gov/pubmed/35364120
http://dx.doi.org/10.1016/j.jconrel.2022.03.051

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