Porcine Gasdermin D Is a Substrate of Caspase-1 and an Executioner of Pyroptosis

Gasdermin (GSDM) family proteins were recently identified as the executioner of pyroptosis. The mechanism of pyroptosis mediated by gasdermin D (GSDMD) (a member of GSDM family) in humans and mice is well understood. In pyroptosis, mouse and human GSDMDs are cleaved by activated proinflammatory casp...

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Detalles Bibliográficos
Autores principales: Song, Yueyang, Song, Jiameng, Wang, Meng, Wang, Junwei, Ma, Bo, Zhang, Wenlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964005/
https://www.ncbi.nlm.nih.gov/pubmed/35359964
http://dx.doi.org/10.3389/fimmu.2022.828911

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964005/
https://www.ncbi.nlm.nih.gov/pubmed/35359964
http://dx.doi.org/10.3389/fimmu.2022.828911

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