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Porcine Gasdermin D Is a Substrate of Caspase-1 and an Executioner of Pyroptosis
Gasdermin (GSDM) family proteins were recently identified as the executioner of pyroptosis. The mechanism of pyroptosis mediated by gasdermin D (GSDMD) (a member of GSDM family) in humans and mice is well understood. In pyroptosis, mouse and human GSDMDs are cleaved by activated proinflammatory casp...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964005/ https://www.ncbi.nlm.nih.gov/pubmed/35359964 http://dx.doi.org/10.3389/fimmu.2022.828911 |