Transcriptomics Reveals the Mevalonate and Cholesterol Pathways Blocking as Part of the Bacterial Cyclodipeptides Cytotoxic Effects in HeLa Cells of Human Cervix Adenocarcinoma

The incidence of human cervix adenocarcinoma (CC) caused by papillomavirus genome integration into the host chromosome is the third most common cancer among women. Bacterial cyclodipeptides (CDPs) exert cytotoxic effects in human cervical cancer HeLa cells, primarily by blocking the PI3K/Akt/mTOR pa...

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Detalles Bibliográficos
Autores principales: Lázaro-Mixteco, Pedro E., González-Coronel, José M., Hernández-Padilla, Laura, Martínez-Alcantar, Lorena, Martínez-Carranza, Enrique, López-Bucio, Jesús Salvador, Guevara-García, Ángel A., Campos-García, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964019/
https://www.ncbi.nlm.nih.gov/pubmed/35359411
http://dx.doi.org/10.3389/fonc.2022.790537

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