Sustained Downregulation of Vascular Smooth Muscle Acta2 After Transient Angiotensin II Infusion: A New Model of “Vascular Memory”

BACKGROUND: Activation of the renin-angiotensin-aldosterone system (RAAS) plays a critical role in the development of hypertension. Published evidence on a putative “memory effect” of AngII on the vascular components is however scarce. AIM: To evaluate the long-term effects of transient exposure to...

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Detalles Bibliográficos
Autores principales: Pothen, Lucie, Verdoy, Roxane, De Mulder, Delphine, Esfahani, Hrag, Farah, Charlotte, Michel, Lauriane Y. M., Dei Zotti, Flavia, Bearzatto, Bertrand, Ambroise, Jerome, Bouzin, Caroline, Dessy, Chantal, Balligand, Jean-Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964264/
https://www.ncbi.nlm.nih.gov/pubmed/35360022
http://dx.doi.org/10.3389/fcvm.2022.854361

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