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Paeoniflorin Ameliorates Skeletal Muscle Atrophy in Chronic Kidney Disease via AMPK/SIRT1/PGC-1α-Mediated Oxidative Stress and Mitochondrial Dysfunction

Skeletal muscle atrophy is a common and serious complication of chronic kidney disease (CKD). Oxidative stress and mitochondrial dysfunction are involved in the pathogenesis of muscle atrophy. The aim of this study was to explore the effects and mechanisms of paeoniflorin on CKD skeletal muscle atro...

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Detalles Bibliográficos
Autores principales:	Li, Qiang, Wu, Jing, Huang, Jiawen, Hu, Rong, You, Haiyan, Liu, Lingyu, Wang, Dongtao, Wei, Lianbo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964350/ https://www.ncbi.nlm.nih.gov/pubmed/35370668 http://dx.doi.org/10.3389/fphar.2022.859723

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