Physicochemical Properties and Methods of Analysis of Vildagliptin (Review)

Vildagliptin is an oral agent which is a member of a new class of hypoglycemic drugs, dipeptidylpeptidase-4 (DPP-4) inhibitors. This review presents the physicochemical properties of vildagliptin and assesses analysis methods for its estimation in substances, medicinal formulations, and biological m...

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Detalles Bibliográficos
Autores principales: Polyakova, E. B., Sabirzyanov, D. R., Prozorova, N. A., Foteeva, A. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964380/
https://www.ncbi.nlm.nih.gov/pubmed/35370321
http://dx.doi.org/10.1007/s11094-022-02606-1
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author Polyakova, E. B.
Sabirzyanov, D. R.
Prozorova, N. A.
Foteeva, A. V.
author_facet Polyakova, E. B.
Sabirzyanov, D. R.
Prozorova, N. A.
Foteeva, A. V.
author_sort Polyakova, E. B.
collection PubMed
description Vildagliptin is an oral agent which is a member of a new class of hypoglycemic drugs, dipeptidylpeptidase-4 (DPP-4) inhibitors. This review presents the physicochemical properties of vildagliptin and assesses analysis methods for its estimation in substances, medicinal formulations, and biological media. These are chromatographic, spectrophotometric, electrochemical and other analysis methods. The material presented may be useful for developing new methods for analysis of medicinal formulations containing vildagliptin. The most widely used method for assay of vildagliptin is HPLC.
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spelling pubmed-89643802022-03-30 Physicochemical Properties and Methods of Analysis of Vildagliptin (Review) Polyakova, E. B. Sabirzyanov, D. R. Prozorova, N. A. Foteeva, A. V. Pharm Chem J Article Vildagliptin is an oral agent which is a member of a new class of hypoglycemic drugs, dipeptidylpeptidase-4 (DPP-4) inhibitors. This review presents the physicochemical properties of vildagliptin and assesses analysis methods for its estimation in substances, medicinal formulations, and biological media. These are chromatographic, spectrophotometric, electrochemical and other analysis methods. The material presented may be useful for developing new methods for analysis of medicinal formulations containing vildagliptin. The most widely used method for assay of vildagliptin is HPLC. Springer US 2022-03-30 2022 /pmc/articles/PMC8964380/ /pubmed/35370321 http://dx.doi.org/10.1007/s11094-022-02606-1 Text en © Springer Science+Business Media, LLC, part of Springer Nature 2022 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Polyakova, E. B.
Sabirzyanov, D. R.
Prozorova, N. A.
Foteeva, A. V.
Physicochemical Properties and Methods of Analysis of Vildagliptin (Review)
title Physicochemical Properties and Methods of Analysis of Vildagliptin (Review)
title_full Physicochemical Properties and Methods of Analysis of Vildagliptin (Review)
title_fullStr Physicochemical Properties and Methods of Analysis of Vildagliptin (Review)
title_full_unstemmed Physicochemical Properties and Methods of Analysis of Vildagliptin (Review)
title_short Physicochemical Properties and Methods of Analysis of Vildagliptin (Review)
title_sort physicochemical properties and methods of analysis of vildagliptin (review)
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964380/
https://www.ncbi.nlm.nih.gov/pubmed/35370321
http://dx.doi.org/10.1007/s11094-022-02606-1
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