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Multi-Scale Computational Modeling of Spatial Calcium Handling From Nanodomain to Whole-Heart: Overview and Perspectives

Regulation of intracellular calcium is a critical component of cardiac electrophysiology and excitation-contraction coupling. The calcium spark, the fundamental element of the intracellular calcium transient, is initiated in specialized nanodomains which co-locate the ryanodine receptors and L-type...

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Detalles Bibliográficos
Autores principales:	Colman, Michael A., Alvarez-Lacalle, Enrique, Echebarria, Blas, Sato, Daisuke, Sutanto, Henry, Heijman, Jordi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964409/ https://www.ncbi.nlm.nih.gov/pubmed/35370783 http://dx.doi.org/10.3389/fphys.2022.836622

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