Stratification of chemotherapy-treated stage III colorectal cancer patients using multiplexed imaging and single-cell analysis of T-cell populations

Colorectal cancer (CRC) has one of the highest cancer incidences and mortality rates. In stage III, postoperative chemotherapy benefits <20% of patients, while more than 50% will develop distant metastases. Biomarkers for identification of patients at increased risk of disease recurrence followin...

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Detalles Bibliográficos
Autores principales: Stachtea, Xanthi, Loughrey, Maurice B., Salvucci, Manuela, Lindner, Andreas U., Cho, Sanghee, McDonough, Elizabeth, Sood, Anup, Graf, John, Santamaria-Pang, Alberto, Corwin, Alex, Laurent-Puig, Pierre, Dasgupta, Sonali, Shia, Jinru, Owens, Jonathan R., Abate, Samantha, Van Schaeybroeck, Sandra, Lawler, Mark, Prehn, Jochen H. M., Ginty, Fiona, Longley, Daniel B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964416/
https://www.ncbi.nlm.nih.gov/pubmed/34732839
http://dx.doi.org/10.1038/s41379-021-00953-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964416/
https://www.ncbi.nlm.nih.gov/pubmed/34732839
http://dx.doi.org/10.1038/s41379-021-00953-0

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