Structure-Property Relationship for Different Mesoporous Silica Nanoparticles and its Drug Delivery Applications: A Review

Mesoporous silica nanoparticles (MSNs) are widely used as a promising candidate for drug delivery applications due to silica’s favorable biocompatibility, thermal stability, and chemical properties. Silica’s unique mesoporous structure allows for effective drug loading and controlled release at the...

Descripción completa

Detalles Bibliográficos
Autores principales: Kazemzadeh, Parya, Sayadi, Khalil, Toolabi, Ali, Sayadi, Jalil, Zeraati, Malihe, Chauhan, Narendra Pal Singh, Sargazi, Ghasem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964429/
https://www.ncbi.nlm.nih.gov/pubmed/35372272
http://dx.doi.org/10.3389/fchem.2022.823785
_version_ 1784678216020000768
author Kazemzadeh, Parya
Sayadi, Khalil
Toolabi, Ali
Sayadi, Jalil
Zeraati, Malihe
Chauhan, Narendra Pal Singh
Sargazi, Ghasem
author_facet Kazemzadeh, Parya
Sayadi, Khalil
Toolabi, Ali
Sayadi, Jalil
Zeraati, Malihe
Chauhan, Narendra Pal Singh
Sargazi, Ghasem
author_sort Kazemzadeh, Parya
collection PubMed
description Mesoporous silica nanoparticles (MSNs) are widely used as a promising candidate for drug delivery applications due to silica’s favorable biocompatibility, thermal stability, and chemical properties. Silica’s unique mesoporous structure allows for effective drug loading and controlled release at the target site. In this review, we have discussed various methods of MSNs’ mechanism, properties, and its drug delivery applications. As a result, we came to the conclusion that more in vivo biocompatibility studies, toxicity studies, bio-distribution studies and clinical research are essential for MSN advancement.
format Online
Article
Text
id pubmed-8964429
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-89644292022-03-31 Structure-Property Relationship for Different Mesoporous Silica Nanoparticles and its Drug Delivery Applications: A Review Kazemzadeh, Parya Sayadi, Khalil Toolabi, Ali Sayadi, Jalil Zeraati, Malihe Chauhan, Narendra Pal Singh Sargazi, Ghasem Front Chem Chemistry Mesoporous silica nanoparticles (MSNs) are widely used as a promising candidate for drug delivery applications due to silica’s favorable biocompatibility, thermal stability, and chemical properties. Silica’s unique mesoporous structure allows for effective drug loading and controlled release at the target site. In this review, we have discussed various methods of MSNs’ mechanism, properties, and its drug delivery applications. As a result, we came to the conclusion that more in vivo biocompatibility studies, toxicity studies, bio-distribution studies and clinical research are essential for MSN advancement. Frontiers Media S.A. 2022-03-14 /pmc/articles/PMC8964429/ /pubmed/35372272 http://dx.doi.org/10.3389/fchem.2022.823785 Text en Copyright © 2022 Kazemzadeh, Sayadi, Toolabi, Sayadi, Zeraati, Chauhan and Sargazi. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Chemistry
Kazemzadeh, Parya
Sayadi, Khalil
Toolabi, Ali
Sayadi, Jalil
Zeraati, Malihe
Chauhan, Narendra Pal Singh
Sargazi, Ghasem
Structure-Property Relationship for Different Mesoporous Silica Nanoparticles and its Drug Delivery Applications: A Review
title Structure-Property Relationship for Different Mesoporous Silica Nanoparticles and its Drug Delivery Applications: A Review
title_full Structure-Property Relationship for Different Mesoporous Silica Nanoparticles and its Drug Delivery Applications: A Review
title_fullStr Structure-Property Relationship for Different Mesoporous Silica Nanoparticles and its Drug Delivery Applications: A Review
title_full_unstemmed Structure-Property Relationship for Different Mesoporous Silica Nanoparticles and its Drug Delivery Applications: A Review
title_short Structure-Property Relationship for Different Mesoporous Silica Nanoparticles and its Drug Delivery Applications: A Review
title_sort structure-property relationship for different mesoporous silica nanoparticles and its drug delivery applications: a review
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964429/
https://www.ncbi.nlm.nih.gov/pubmed/35372272
http://dx.doi.org/10.3389/fchem.2022.823785
work_keys_str_mv AT kazemzadehparya structurepropertyrelationshipfordifferentmesoporoussilicananoparticlesanditsdrugdeliveryapplicationsareview
AT sayadikhalil structurepropertyrelationshipfordifferentmesoporoussilicananoparticlesanditsdrugdeliveryapplicationsareview
AT toolabiali structurepropertyrelationshipfordifferentmesoporoussilicananoparticlesanditsdrugdeliveryapplicationsareview
AT sayadijalil structurepropertyrelationshipfordifferentmesoporoussilicananoparticlesanditsdrugdeliveryapplicationsareview
AT zeraatimalihe structurepropertyrelationshipfordifferentmesoporoussilicananoparticlesanditsdrugdeliveryapplicationsareview
AT chauhannarendrapalsingh structurepropertyrelationshipfordifferentmesoporoussilicananoparticlesanditsdrugdeliveryapplicationsareview
AT sargazighasem structurepropertyrelationshipfordifferentmesoporoussilicananoparticlesanditsdrugdeliveryapplicationsareview

Ejemplares similares