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PLK1 Mitigates Intervertebral Disc Degeneration by Delaying Senescence of Nucleus Pulposus Cells

Intervertebral disc degeneration (IVDD) is the primary cause of low back pain; however, the molecular mechanisms involved in the pathogenesis of IVDD are not fully understood. Polo-like kinase 1 (PLK1) plays numerous roles in the cell cycle, including in cell proliferation and senescence. To investi...

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Detalles Bibliográficos
Autores principales:	Zhang, Zhenlei, Huang, Yizhen, Xu, Nizhen, Wang, Jianle, Yao, Teng, Xu, Yining, Qiao, Di, Gao, Jun, Shen, Shuying, Ma, Jianjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964438/ https://www.ncbi.nlm.nih.gov/pubmed/35372354 http://dx.doi.org/10.3389/fcell.2022.819262

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