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Systems of conductive skin for power transfer in clinical applications

The primary aim of this article is to review the clinical challenges related to the supply of power in implanted left ventricular assist devices (LVADs) by means of transcutaneous drivelines. In effect of that, we present the preventive measures and post-operative protocols that are regularly employ...

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Autores principales: Kourouklis, Andreas P., Kaemmel, Julius, Wu, Xi, Potapov, Evgenij, Cesarovic, Nikola, Ferrari, Aldo, Starck, Christoph, Falk, Volkmar, Mazza, Edoardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964546/
https://www.ncbi.nlm.nih.gov/pubmed/34477935
http://dx.doi.org/10.1007/s00249-021-01568-8
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author Kourouklis, Andreas P.
Kaemmel, Julius
Wu, Xi
Potapov, Evgenij
Cesarovic, Nikola
Ferrari, Aldo
Starck, Christoph
Falk, Volkmar
Mazza, Edoardo
author_facet Kourouklis, Andreas P.
Kaemmel, Julius
Wu, Xi
Potapov, Evgenij
Cesarovic, Nikola
Ferrari, Aldo
Starck, Christoph
Falk, Volkmar
Mazza, Edoardo
author_sort Kourouklis, Andreas P.
collection PubMed
description The primary aim of this article is to review the clinical challenges related to the supply of power in implanted left ventricular assist devices (LVADs) by means of transcutaneous drivelines. In effect of that, we present the preventive measures and post-operative protocols that are regularly employed to address the leading problem of driveline infections. Due to the lack of reliable wireless solutions for power transfer in LVADs, the development of new driveline configurations remains at the forefront of different strategies that aim to power LVADs in a less destructive manner. To this end, skin damage and breach formation around transcutaneous LVAD drivelines represent key challenges before improving the current standard of care. For this reason, we assess recent strategies on the surface functionalization of LVAD drivelines, which aim to limit the incidence of driveline infection by directing the responses of the skin tissue. Moreover, we propose a class of power transfer systems that could leverage the ability of skin tissue to effectively heal short diameter wounds. In this direction, we employed a novel method to generate thin conductive wires of controllable surface topography with the potential to minimize skin disruption and eliminate the problem of driveline infections. Our initial results suggest the viability of the small diameter wires for the investigation of new power transfer systems for LVADs. Overall, this review uniquely compiles a diverse number of topics with the aim to instigate new research ventures on the design of power transfer systems for IMDs, and specifically LVADs.
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spelling pubmed-89645462022-04-07 Systems of conductive skin for power transfer in clinical applications Kourouklis, Andreas P. Kaemmel, Julius Wu, Xi Potapov, Evgenij Cesarovic, Nikola Ferrari, Aldo Starck, Christoph Falk, Volkmar Mazza, Edoardo Eur Biophys J Review The primary aim of this article is to review the clinical challenges related to the supply of power in implanted left ventricular assist devices (LVADs) by means of transcutaneous drivelines. In effect of that, we present the preventive measures and post-operative protocols that are regularly employed to address the leading problem of driveline infections. Due to the lack of reliable wireless solutions for power transfer in LVADs, the development of new driveline configurations remains at the forefront of different strategies that aim to power LVADs in a less destructive manner. To this end, skin damage and breach formation around transcutaneous LVAD drivelines represent key challenges before improving the current standard of care. For this reason, we assess recent strategies on the surface functionalization of LVAD drivelines, which aim to limit the incidence of driveline infection by directing the responses of the skin tissue. Moreover, we propose a class of power transfer systems that could leverage the ability of skin tissue to effectively heal short diameter wounds. In this direction, we employed a novel method to generate thin conductive wires of controllable surface topography with the potential to minimize skin disruption and eliminate the problem of driveline infections. Our initial results suggest the viability of the small diameter wires for the investigation of new power transfer systems for LVADs. Overall, this review uniquely compiles a diverse number of topics with the aim to instigate new research ventures on the design of power transfer systems for IMDs, and specifically LVADs. Springer International Publishing 2021-09-03 2022 /pmc/articles/PMC8964546/ /pubmed/34477935 http://dx.doi.org/10.1007/s00249-021-01568-8 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Review
Kourouklis, Andreas P.
Kaemmel, Julius
Wu, Xi
Potapov, Evgenij
Cesarovic, Nikola
Ferrari, Aldo
Starck, Christoph
Falk, Volkmar
Mazza, Edoardo
Systems of conductive skin for power transfer in clinical applications
title Systems of conductive skin for power transfer in clinical applications
title_full Systems of conductive skin for power transfer in clinical applications
title_fullStr Systems of conductive skin for power transfer in clinical applications
title_full_unstemmed Systems of conductive skin for power transfer in clinical applications
title_short Systems of conductive skin for power transfer in clinical applications
title_sort systems of conductive skin for power transfer in clinical applications
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964546/
https://www.ncbi.nlm.nih.gov/pubmed/34477935
http://dx.doi.org/10.1007/s00249-021-01568-8
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