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Complement induces podocyte pyroptosis in membranous nephropathy by mediating mitochondrial dysfunction
Podocyte damage mediated by in situ complement activation in the glomeruli is a key factor in the pathogenesis of membranous nephropathy (MN), but the molecular mechanism has not been fully elucidated. Pyroptosis is a special type of programmed cell death, mediate inflammatory response and induce ti...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964685/ https://www.ncbi.nlm.nih.gov/pubmed/35351877 http://dx.doi.org/10.1038/s41419-022-04737-5 |