Complement induces podocyte pyroptosis in membranous nephropathy by mediating mitochondrial dysfunction

Podocyte damage mediated by in situ complement activation in the glomeruli is a key factor in the pathogenesis of membranous nephropathy (MN), but the molecular mechanism has not been fully elucidated. Pyroptosis is a special type of programmed cell death, mediate inflammatory response and induce ti...

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Detalles Bibliográficos
Autores principales: Wang, Hui, Lv, Daoyuan, Jiang, Song, Hou, Qing, Zhang, Lei, Li, Shen, Zhu, Xiaodong, Xu, Xiaodong, Wen, Jianqiang, Zeng, Caihong, Zhang, Mingchao, Yang, Fan, Chen, Zhaohong, Zheng, Chunxia, Li, Jing, Zen, Ke, Liu, Zhihong, Li, Limin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964685/
https://www.ncbi.nlm.nih.gov/pubmed/35351877
http://dx.doi.org/10.1038/s41419-022-04737-5

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