Knowledge graph-based recommendation framework identifies drivers of resistance in EGFR mutant non-small cell lung cancer

Resistance to EGFR inhibitors (EGFRi) presents a major obstacle in treating non-small cell lung cancer (NSCLC). One of the most exciting new ways to find potential resistance markers involves running functional genetic screens, such as CRISPR, followed by manual triage of significantly enriched gene...

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Detalles Bibliográficos
Autores principales: Gogleva, Anna, Polychronopoulos, Dimitris, Pfeifer, Matthias, Poroshin, Vladimir, Ughetto, Michaël, Martin, Matthew J., Thorpe, Hannah, Bornot, Aurelie, Smith, Paul D., Sidders, Ben, Dry, Jonathan R., Ahdesmäki, Miika, McDermott, Ultan, Papa, Eliseo, Bulusu, Krishna C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964738/
https://www.ncbi.nlm.nih.gov/pubmed/35351890
http://dx.doi.org/10.1038/s41467-022-29292-7

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