Crystal structure and cellular functions of uPAR dimer

Receptor dimerization of urokinase-type plasminogen activator receptor (uPAR) was previously identified at protein level and on cell surface. Recently, a dimeric form of mouse uPAR isoform 2 was proposed to induce kidney disease. Here, we report the crystal structure of human uPAR dimer at 2.96 Å. T...

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Detalles Bibliográficos
Autores principales: Yu, Shujuan, Sui, Yaqun, Wang, Jiawei, Li, Yongdong, Li, Hanlin, Cao, Yingping, Chen, Liqing, Jiang, Longguang, Yuan, Cai, Huang, Mingdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964761/
https://www.ncbi.nlm.nih.gov/pubmed/35351875
http://dx.doi.org/10.1038/s41467-022-29344-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964761/
https://www.ncbi.nlm.nih.gov/pubmed/35351875
http://dx.doi.org/10.1038/s41467-022-29344-y

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