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Crystal structure and cellular functions of uPAR dimer

Receptor dimerization of urokinase-type plasminogen activator receptor (uPAR) was previously identified at protein level and on cell surface. Recently, a dimeric form of mouse uPAR isoform 2 was proposed to induce kidney disease. Here, we report the crystal structure of human uPAR dimer at 2.96 Å. T...

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Detalles Bibliográficos
Autores principales:	Yu, Shujuan, Sui, Yaqun, Wang, Jiawei, Li, Yongdong, Li, Hanlin, Cao, Yingping, Chen, Liqing, Jiang, Longguang, Yuan, Cai, Huang, Mingdong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964761/ https://www.ncbi.nlm.nih.gov/pubmed/35351875 http://dx.doi.org/10.1038/s41467-022-29344-y

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