Effects of APOE4 allelic dosage on lipidomic signatures in the entorhinal cortex of aged mice

Apolipoprotein E ε4 (APOE4) is the primary genetic risk factor for the late-onset form of Alzheimer’s disease (AD). Although the reason for this association is not completely understood, researchers have uncovered numerous effects of APOE4 expression on AD-relevant brain processes, including amyloid...

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Detalles Bibliográficos
Autores principales: Miranda, André Miguel, Ashok, Archana, Chan, Robin Barry, Zhou, Bowen, Xu, Yimeng, McIntire, Laura Beth, Area-Gomez, Estela, Di Paolo, Gilbert, Duff, Karen E., Oliveira, Tiago Gil, Nuriel, Tal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964762/
https://www.ncbi.nlm.nih.gov/pubmed/35351864
http://dx.doi.org/10.1038/s41398-022-01881-6

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