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Downregulation of MEIS1 mediated by ELFN1-AS1/EZH2/DNMT3a axis promotes tumorigenesis and oxaliplatin resistance in colorectal cancer

Oxaliplatin is widely used in the frontline treatment of colorectal cancer (CRC), but an estimated 50% of patients will eventually stop responding to treatment due to acquired resistance. This study revealed that diminished MEIS1 expression was detected in CRC and harmed the survival of CRC patients...

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Detalles Bibliográficos
Autores principales:	Li, Yimin, Gan, Yaqi, Liu, Jiaxin, Li, Juanni, Zhou, Zhengwei, Tian, Ruotong, Sun, Ruizheng, Liu, Jiaqi, Xiao, Qing, Li, Yuanyuan, Lu, Pengyan, Peng, Yulong, Peng, Yuqian, Shu, Guang, Yin, Gang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964798/ https://www.ncbi.nlm.nih.gov/pubmed/35351858 http://dx.doi.org/10.1038/s41392-022-00902-6

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