Matrix stiffness exacerbates the proinflammatory responses of vascular smooth muscle cell through the DDR1-DNMT1 mechanotransduction axis

Vascular smooth muscle cell (vSMC) is highly plastic as its phenotype can change in response to mechanical cues inherent to the extracellular matrix (ECM). VSMC may be activated from its quiescent contractile phenotype to a proinflammatory phenotype, whereby the cell secretes chemotactic and inflamm...

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Detalles Bibliográficos
Autores principales: Wang, Jin, Xie, Si-an, Li, Ning, Zhang, Tao, Yao, Weijuan, Zhao, Hucheng, Pang, Wei, Han, Lili, Liu, Jiayu, Zhou, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964982/
https://www.ncbi.nlm.nih.gov/pubmed/35386458
http://dx.doi.org/10.1016/j.bioactmat.2022.01.012

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