BRD7 Stabilizes P53 via Dephosphorylation of MDM2 to Inhibit Tumor Growth in Breast Cancer Harboring Wild-type P53

Bromodomain-containing protein 7 (BRD7) was found to be down-expressed in nasopharyngeal carcinoma as well as breast cancer and to function as a potential tumor suppressor. BRD7 interacts with p53 and is required for p53-dependent oncogene-induced senescence. However, the mechanism how BRD7 function...

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Detalles Bibliográficos
Autores principales: Luo, Yanwei, Wang, Xinye, Niu, Weihong, Zhou, Yao, Li, Mengna, Ma, Jinqi, Yang, Jing, Fan, Songqing, Zeng, Zhaoyang, Xiong, Wei, Li, Xiaoling, Li, Guiyuan, Xiao, Jidong, Zhou, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965117/
https://www.ncbi.nlm.nih.gov/pubmed/35371302
http://dx.doi.org/10.7150/jca.67447

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