Coagulation factor protein abundance in the pre-septic state predicts coagulopathic activities that arise during late-stage murine sepsis

BACKGROUND: Although sepsis accounts for 1 in 5 deaths globally, few molecular therapies exist for this condition. The development of effective biomarkers and treatments for sepsis requires a more complete understanding of host responses and pathogenic mechanisms at early stages of disease to minimi...

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Detalles Bibliográficos
Autores principales: Heithoff, Douglas M., Pimienta, Genaro, Mahan, Scott P., Yang, Won Ho, Le, Dzung T., House, John K., Marth, Jamey D., Smith, Jeffrey W., Mahan, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965145/
https://www.ncbi.nlm.nih.gov/pubmed/35349828
http://dx.doi.org/10.1016/j.ebiom.2022.103965

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