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Mechanistic origin of partial agonism of tetrahydrocannabinol for cannabinoid receptors
Cannabinoid receptor 1 (CB(1)) is a therapeutically relevant drug target for controlling pain, obesity, and other central nervous system disorders. However, full agonists and antagonists of CB(1) have been reported to cause serious side effects in patients. Therefore, partial agonists have emerged a...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965160/ https://www.ncbi.nlm.nih.gov/pubmed/35227761 http://dx.doi.org/10.1016/j.jbc.2022.101764 |