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Mechanistic origin of partial agonism of tetrahydrocannabinol for cannabinoid receptors

Cannabinoid receptor 1 (CB(1)) is a therapeutically relevant drug target for controlling pain, obesity, and other central nervous system disorders. However, full agonists and antagonists of CB(1) have been reported to cause serious side effects in patients. Therefore, partial agonists have emerged a...

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Detalles Bibliográficos
Autores principales:	Dutta, Soumajit, Selvam, Balaji, Das, Aditi, Shukla, Diwakar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965160/ https://www.ncbi.nlm.nih.gov/pubmed/35227761 http://dx.doi.org/10.1016/j.jbc.2022.101764

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